My research focuses on immunometabolism in T cells, macrophages and dendritic cells. My laboratory also explores how the metabolic crosstalk between cancer cells and tumor-infiltrating immune cells shapes the immunosuppressive microenvironment that helps tumors evade immune clearance. Our ultimate goal is to exploit this knowledge to develop interventions to reprogram the tumor microenvironment, reverse immunosuppression and broaden and boost the efficacy of cancer immunotherapy. My work is establishing a fundamental understanding on how tumor cells evade immunosurveillance through their metabolism, and how we can preprogram the metabolic machinery of immune cells to improve immunotherapy. My work is also delineating links between metabolic processes, signaling cascades and epigenetic programming in the activation and differentiation of immune cells.