Real-time tracking of redox metabolism in living cells and in vivo with genetically encoded sensors

SEMINAR -CANCELED 

Yuzheng ZHAO

East China University of Science and Technology, Shanghai, China.

Currently methodologies with quantitative, microscopic and dynamic potential are greatly desired by biomedical research. Particularly, spatiotemporal imaging cellular metabolism provides indispensable tools for solving complex biological questions. Recently we developed a series of genetically encoded fluorescent sensors for NADH, NAD+ and their ratio, which can be targeted to different cells, various subcellular organelles and animal models and used to monitor and image cellular metabolism with high spatial solutions and in real time.  

Hosts: Kristina Schoonjans and Johan Auwerx (EPFL)

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